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Use Case

Pharma & Biotech

Streamline drug discovery database with precision SAR and pharmacological data from GOSTAR®

GOSTAR® allows us, effectively, to enter an area of biological and chemical space that wouldn’t be possible otherwise. Jonny Wray (CTO, E-therapeutics)
e-therapuetics

Accelerate R&D with GOSTAR®

Utilize the expansive SAR data by GOSTAR® for pharmaceutical R&D acceleration. Our precision inherent database, acquired over 20 years experience in compiling critical data, houses over 9.7 chemical structures and 33+ million SAR data points. The data has been meticulously curated to support your drug discovery and development. Optimize lead selection with reliable data, improve hit-to-lead conversion, and enhance your molecule’s progression through the pipeline. This enables the scientists to get the answers that they need faster and with more certainty.

GOSTAR® Database by the Numbers

10

Chemical structures

120

Abstracts & Conferences

33

SAR Data

78

Companies & Institutes

77

Biological Targets

4

Patents Screened

9.7

Chemical structures

33

SAR Data

120

Abstracts & Conferences

78

Companies & Institutes

77

Biological Targets

4

Patents Screened

Predict Adverse Events

Advance in your safety assessments with confidence by integrating the extensive toxicity and ADME profiles available in GOSTAR. Proactively identify potential adverse effects, streamline your compound’s evaluation process, and navigate the regulatory landscape with data that backs your drug’s safety profile. GOSTAR® supports your commitment to developing safer therapeutic solutions.

Derive Strategic Insights

GOSTAR® offers strategic insights with its extensive medicinal chemistry database. Gain access to a wide array of data, including detailed patent analysis and journal extracts. This database is tailored to enhance pharmaceutical research, providing essential information to guide decision-making and support the development of new therapeutics. GOSTAR® is your resource for navigating the complex landscape of drug discovery and market entry.

Derive Strategic Insights

GOSTAR® offers strategic insights with its extensive medicinal chemistry database. Gain access to a wide array of data, including detailed patent analysis and journal extracts. This database is tailored to enhance pharmaceutical research, providing essential information to guide decision-making and support the development of new therapeutics. GOSTAR® is your resource for navigating the complex landscape of drug discovery and market entry.

The Tools to Provide Clarity

GOSTAR® enables early discovery in drug development by providing normalized compound–target affinity data as well as comprehensive pharmacokinetic, efficacy, metabolic, and toxicity profiles. It enables medicinal chemists to build powerful searches which provide detailed insight into the entire pharmaceutical space. Find a wealth of data in GOSTAR®.

The drug-target interaction heatmap facilitates decision-making about the potential off-target activity of drug candidates early in drug development and drug repurposing workflows. GOSTAR® presents these findings in a visually intuitive manner, allowing end-users to easily interpret the data and draw conclusions. Unlock rapid insights from data with GOSTAR®.

Matched molecular pair analysis is a powerful tool for determining which compound to design and test next. Computer algorithms analyse data in an unbiased manner to create design guidelines that will allow medicinal chemists to propose better compounds that reduce the number of design cycles. GOSTAR® is your key to your groundbreaking compound design and analysing activity landscapes across compound datasets. Design more effective compounds with GOSTAR®.

Lipophilicity is an important factor in determining the binding affinity of a drug to protein targets, as well as influencing ADMET properties. As a result, the combination of high target potency and high lipophilicity may increase the likelihood of ADMET-related attrition. Therefore, medicinal chemistry optimization needs to be balanced and multidimensional. GOSTAR® empowers medicinal chemists to efficiently explore the property space of compounds against a variety of bioactivity endpoints. Discover your next breakthrough with GOSTAR®.

What our customers say

GOSTAR® helps us analyze the competitive landscape, understand what’s out there, and in some instances, helps us to build models based on known information as well as train systems to assess how well we are doing at the curation process.

Bryce Allen
CEO/Co-founder, Differentiated Therapeutics

Knowledge Hub

Analyzer in GOSTAR®: Interactive Property Space Exploration

GOSTAR® is an integrated platform of various standalone databases with cross-indexing of chemical compounds of…

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GOSTAR® Updates: The Latest Feature Enhancements

Modern-day medicinal and computational chemists thrive in a data-rich environment, constantly seeking to uncover untapped…

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GOSTAR®: the largest online medicinal chemistry intelligence database

In medicinal chemistry, the relationship between molecular structure of a compound and its biological activity…

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More use cases

AI / ML

Boost AI-driven drug discovery with GOSTAR®. It provides a highly normalized, QMS-ISO certified quality data set that can be used to train ML algorithms and help drive the search for novel compounds.

Academia

Academic researchers and educators benefit from comprehensive SAR and pharmacology data in GOSTAR®, supporting them to advance in research, facilitating innovative studies, and enabling publication in top-tier journals.

Accelerate your project with GOSTAR®

Detail your project goals, and together, we can shape the future of therapeutic discovery.

For evaluation & paid license requests:
gostardb@excelra.com

For product queries & support:
support.gostar@excelra.com

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